WJPPS Citation

Login

Search

News & Updation

  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  
  • New Impact Factor
  • WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

  • WJPPS: MARCH ISSUE PUBLISHED
  • March Issue has been successfully launched on 1 March 2024.

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • Scope Indexed
  • WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

Abstract

ANALGESIC AND ANTI-INFLAMMATORY ACTIVITY OF MILAGARANAI VER CHOORANAM (ROOT OF TODDALIA ASIATICA) IN RODENTS

A.Karthikeyan*, K.S.Sivasaravanan , I.S.Gnanavel, D.Prakash,V.Velpandian

ABSTRACT

Milagaranai Ver Chooranam(root of Toddalia asiatica)is one of the Siddha herbal drug, which has been indicated for its analgesic and antiinflammatory properties. The aim of this present study is to validate Analgesic, acute and chronic anti-inflammatory activity of Milagaranai Ver Chooranamat the doses of 100 mg/kg and200 mg/kgbody weight in experimental animals. Analgesic activity was evaluated by hot plate method in Swiss albino mice; acute and chronic anti-inflammatory activity was evaluated by carrageenaninduced paw oedema and cotton pellet granuloma in Wistar albino rats respectively. Diclofenac sodium and Ibuprofen were employed as reference drugs for analgesic and anti-inflammatory studies.The animals were randomized into 4 groups (n=6). Control group received vehicle only. MVC 100 and MVC200 significantly inhibited pain, carrageenan induced paw oedema and reduced the weight of cotton pellet granuloma. These effects are more significant at the dose of 200 mg compared to MVC 100mg dose level which showed the dose dependent activity of MVC.Our results confirm the traditional use of Milagaranai Ver Chooranam as an analgesic and anti-inflammatory.

Keywords: Analgesic, anti-inflammatory, carrageenan induced oedema, cotton pellet granuloma, Milagaranai Ver Chooranam, Siddha.


[Download Article]     [Download Certifiate]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More