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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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Updated Version

WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

Call for Paper

WJPPS Invited to submit your valuable manuscripts for Coming Issue.

Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

New Impact Factor

WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

Scope Indexed

WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: APRIL ISSUE PUBLISHED

April Issue has been successfully launched on 1 April 2024.

Abstract

EFFECT OF GRINDING SPEED TO PHYSICOCHEMICAL AND SOLUBILITY PROPERTIES OF MEDICINAL COMPOUNDS

Lailatul Masitoh*, Rina Wahyuni and Maria Dona Octavia

ABSTRACT

Solubility is one of the important parameters to achieve medicine concentration towards the systemic circulation to obtain the desired pharmacological response. The solubility of a medicine in water greatly affects the bioavailability of a medicine, so it is very important to increase its solubility and dissolution rate. Because medicines that have low levels of solubility have poor bioavailability. Co-grinding is often used as a technique to increase the solubility of a medicine because there is a reduction in particle size, it can affect the dissolution rate, and it is used to increase the bioavailability of medicinal compounds.

Keywords: medicinal compounds, solubility, physicochemical properties, grinding.

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