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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

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New Impact Factor

WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

Scope Indexed

WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: APRIL ISSUE PUBLISHED

April Issue has been successfully launched on 1 April 2024.

Abstract

ANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR DACLATASVIR BY RP-HPLC METHOD

Prof. Pradip Patil* and Dr. M. Vamsi Krishna

ABSTRACT

A simple, rapid and accurate stability indicating RP-HPLC method was developed for the determination of Daclatsvir. The method was carried out using Column- Kromasil C18 (250×4.6mm, 5μ using ammonium acetate buffer and ACN (40:60, v/v), pH 4.7 as the mobile phase with detection at 335 nm and a flow rate of 1.0 ml/min. The retention time was found to be 6.69 min. The responses were linear in concentrations range of 1-160 μg/ml with correlation coefficient of 0.999. The method was statistically validated for accuracy, precision, linearity, and robustness.

Keywords: Daclatasvir, RP-HPLC Methods, Validation.

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