Abstract

ORAL DISPERSIBLE TABLETS: AN OVERVIEW

K. Prasanthi, B. Hemalatha* and K. Padmalatha

ABSTRACT

Oral route is presently the gold standard in the pharmaceutical industry where it is regarded as the safest, most economical and most convenient method of drug delivery resulting in highest patient compliance. Recent advances in novel drug delivery (NDDS) aims to enhance safety and efficacy of drug molecule by formulating a convenient dosage form for ease of administration and to achieve better patient compliance. One such approach is orodispersible tablets (ODTs). ODTs are a solid unit dosage form, which disintegrates or dissolves rapidly in the mouth without the general requirement for swallowing, the chewing and water. Yet, dysphasia is the most common disadvantage of conventional tablets. To overcome such problems, certain innovative drug delivery systems, like 'Orodispersible Tablets' (ODT) have been developed. The aim of this article is to review the requirements, advantages, limitations, challenges in formulation, various technologies for preparation of ODTs, Evaluation tests of ODTs.

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