WJPPS Citation

Login

Search

News & Updation

  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  
  • New Impact Factor
  • WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

  • WJPPS: MARCH ISSUE PUBLISHED
  • March Issue has been successfully launched on 1 March 2024.

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • Scope Indexed
  • WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

Abstract

CHARACTARIZATION OF CHEMICAL GROUPS AND STUDY OF ANTIOXIDANT, ANTIMICROBIAL AND THROMBOLYTIC ACTIVITIES OF APHANAMIXISPOLYSTACHYA (STEM BARK)

Mohammad Sakim Majumder, Dr. Mohammad SalimHossain, Mohammad NurulAmin, Md. *Mizanur Rahman Moghal, Shimul Banik, Mohammad Mobarak Hossain,

ABSTRACT

The present study was conducted to detect possible chemicals (phytoconstituents), and investigate antioxidant, antimicrobial and thrombolytic activities of the extract of Aphanamixispolystachyastem bark.Phytochemical screening was carried out using the standard test methods of different chemical group. For investigating the antioxidant activity, two complementary test methods namely DPPH free radical scavenging assay and total phenolic content determination were carried out. For the evaluation of in vitro antimicrobial activity, disc diffusion method, and to determine the thrombolytic activity, the method of Prasad et al., 2007 with minor modifications were used. The bark extracts were a rich source of phytochemicals. In DPPH free radical scavenging test,the Carbon tetra chloride soluble fraction showed the highest free radical scavenging activity with IC50 value 19.86μg/ml. while compared to that of the reference standards ascorbic acid .Aphanamixispolystachyawas also found as a good source of total phenolic contents.Morever, the extracts revealed broadspectrum antimicrobial activity at the concentration of 400 μg/disc. By comparing with the negative control the mean clot lysis % was significant (p value <0.0009). Therefore, further studies are suggested to determine the active compounds responsible for the biological activities of the plant extracts.

Keywords: Phytochemical, antioxidant, antimicrobial, thrombolytic, Aphanamixispolystachya.


[Download Article]     [Download Certifiate]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More