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Abstract

ANTI - GLAUCOMATOUS ACTIVITY OF ETHANOLIC EXTRACT OF ERYTHRINA VARIEGATE Lam. LEAVES

R. Krishnaveni*, Dr. S. Karpagam Kumara Sundari and Mr. K.A.S. Mohammed Shafeeq

ABSTRACT

Objective: The aim of this study is to evaluate the anti – glaucomatous activity of Ethanolic extract of Erythrina variegate Lam. Leaves by using carbomer induced glaucoma in rabbits. Methods: Extraction was done by Continuous Hot Percolation method, analyzed by FTIR and HPTLC method and estimated anti - cholinesterase activity (in vitro) and evaluated anti- glaucomatous activity using Rabbit model. Result: 2% ethanolic extract of Erythrina variegate (EEEV) eye drops possess anti – glaucomatous activity. Conclusion: The study affirmed that the ethanolic extract of Erythrina variegate (2%) eye drops produced desirable changes in Intra ocular Pressure (IOP).

Keywords: Anti- glaucomatous activity, Erythrina variegate, EEEV, Carbomer, IOP.


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