Abstract

A SHORT REVIEW ON-GEL AS A TOPICAL DRUG DELIVERY SYSTEM

Aaditya R. Nikam*, Akash H. Patil, Azam Z. Shaikh and D. R. Karnavat

ABSTRACT

Gel preparation delivers well use property and stability in comparison to cream and ointment. Topical gel drug administration is a generalized drug delivery system anywhere in the body through ophthalmic, rectal, vaginal and skin as topical routes. It is superior to observe patient to topical preparations in dealing with chronic skin diseases like fungal infections, acne and psoriasis. Skin is one of the most broad and easily available organs on human body for topical organization and is key route of topical drug delivery system. There is numbers of parameters used to evaluate the gel but most of the time gels are evaluated by following parameters such as pH, homogeneity, grittiness drug content, viscosity, spread ability, skin irritation studies, in-vitro release, Stability.

Keywords: Topical gel, percutaneous penetration, Skin, In-vitro release.