Abstract

SYNTHESIS AND ANTIBACTERIAL ACTIVITY STUDIS OF 2-ARYL BENZOTHIAZOLES AND ITS DERIVATIVES

A.L.V. Ramana Reddy* S.V. Lakshmi Reddy, C Nageswara Reddy,G Chandrasekhar and T.Bhupal Reddy

ABSTRACT

Various benzothiazoles were synthesized by the intramolecular cyclization of thioformanilides using 2,6-dichloro-3,5dicyano-1,4benzoquinone (DDQ) in dichloromethane at ambient temperature in good yields. The structures of all the newly synthesized molecules were assigned by elemental analysis and spectral data. The synthesized compounds were screened for their antibacterial activities strains using Cup plate method.

Keywords: Benzoyl chloride, Lawesson’s reagent, DDQ, Dichloromethane.