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Abstract

A REVIEW ON THE SYNTHESIS AND BIOLOGICAL EVALUATION OF PYRIDO-PYRIMIDINE DERIVATIVES

Atul Sharma,* Ranjeeta Verma, Amit Singh, Abhay Kumar Verma and Shruti Varshney

ABSTRACT

The chemistry of pyrido-pyrimidine is a blossoming field. The utility of pyrimidines as synthon for various biologically active compounds has given momentum to these studies. Pyrimidine and its fused pyrimidine derivatives are a class of heterocyclic scaffolds that demonstrates a broad range of biological and pharmacological activities such as anticancer, anxiolytic, antioxidant, antiviral, antifungal, anticonvulsant, antidepressant, and antibacterial activities. The review article aims to review the work reported and the chemistry and biological activities of pyrido-pyrimidines during past year.

Keywords: Pyrido-Pyrimidines, Therapeutic Potential, Biological evaluation, Strain H37Rv, Mycobacterium Tuberculosis.


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