Abstract

SYSTEMATIC STANDARDIZATION AND PHYSICOCHEMICAL INVESTIGATION OF THE SIDDHA FORMULATION DASADEEPAKINI CHOORANAM IN ACCORDANCE WITH AYUSH GUIDELINE

V. Poorna Pushkala*, S. Mary Princess Sulekha*, S. Meena

ABSTRACT

According to the World Health Organization (WHO), traditional medicine refers to health practices, approaches, knowledge, and beliefs incorporating plant, animal, and mineral-based medicines, spiritual therapies, manual techniques, and exercises, applied singularly or in combination to treat, diagnose, and prevent illnesses or to maintain well-being. If the material being used is of plant origin, then it is called traditional herbal medicine. Many traditional formulations are clinically prescribed by practitioners of traditional medicine under the guidance of theories in traditional medicine, such as Siddha, Ayurveda and Unani in India. Siddha is mainly practiced in south India. This system of medicine is believed to be developed by the Siddhars, the ancient supernatural spiritual saints of India, who developed methods and medications that are believed to strengthen their physical body and thereby their soul, including intense yogic practices and years of fasting and meditation. Siddha formulations become popular cure as an ailment for treating several diseases throughout the globe, as a complementary and alternate medicine. Physicochemical evaluation of the preparation plays vital role in establishing the monograph of the formulation, as it becomes the documentary evidence to substantiate the standards of the preparation. The main aim of the present investigation is to systematically standardize the novel siddha preparation Dasadeepakini Chooranam (DDC) as per AYUSH regulations. Brown colored nature of the drug DDK justifies the purity of the formulation. The results obtained from the physicochemical evaluation revels that the total ash value of DDK was 9.36%, loss on drying value is 3.97% in which acid insoluble ash was found to be 0.26 %. Water soluble extractive value of DDC was 32.41% and the alcohol soluble extractive of DDC was 17.52%. Bulk density and tap density are the two important parameters that signifies the flow property of the formulation. The results of the study projects that bulk density value of DDC were 0.312 g/ml and the corresponding tap density value is 0.511g /ml. Contaminants become the major issue in degrading the biological property of the herbal preparation. The result of specific pathogen analysis of the test sample DDC signifies the absence of the pathogens such as S.aureus, E-coli and Salmonella species. In conclusion the formulation DDC confirms the regulatory requirement as per the recommended standard.

Keywords: Siddha formulation, Physicochemical, Dasadeepakini Chooranam, WHO, AYUSH regulations.