Abstract

STUDY ON ANTIBIOTIC UTILIZATION PATTERN FOR URINARY TRACT INFECTION AT A TERTIARY CARE HOSPITAL IN CALICUT

Siraj Sundaran*, Akhil Reghu, Aswathi Janardhanan K., Chithira M. Das, Tesny Raju and U. C. Ashik Hassan

ABSTRACT

Urinary tract infections (UTI) has been the most commonly encountered bacterial infection that pose a health threat to humans. The study evaluated the prevalence rate of UTI and drug utilization pattern of antibiotics in UTI which was compared to the standard guideline for prescribing. Retrospective randomized observational study design was adopted during the study period of November 2016 to April 2017. A total of 120 medication orders were collected and analyzed. The result showed that prevalence of UTI was higher among female than male. Most of the patients were presenting symptomatic UTI. The most consistent symptom to patient with UTI was fever (36.81%). Hypertension (50%) and diabetes mellitus (56.67%) were the major predisposing factors observed. Out of 60 organisms isolated from the specimens collected Escherichia coli (66.67%) was the common microorganism. Cephalosporins were the most frequently prescribed class of antibiotic (50%) followed by fluoroquinolones (27.50%). Empirical treatment with antibiotics has shown increase in length of stay in hospital when compared to the antibiogram based prescribing.

Keywords: Urinary tract infection, Drug utilization, Antibiotics.