RESPONSE OF SOME MICROORGANISMS TO THERAPEUTIC (NEWLY EFFERVESCENT CIPROFLOXACIN AND CONVENTIONAL BRANDS)
*Ahmed M. A. Msaad
ABSTRACT
Typhoid is an epidemic disease in Sudan and causes morbidity for
many peoples especially in tropical countries.[1] This research aimed to
study the response of (Salmonell typhi and Salmonella para typhi) to
the ciprofloxacin HCl (effervescent formulae ciprofloxacin and
conventional five brands). It is a drug of choice used as an alternative
to chloramphincol.[2] Then the microbiological sensitivity test was
carried out against (Salmonella typhi, Salmonella para typhi) to detect
the response of each one and comparison was held between
conventional and unconventional tablets.[3] The results were found that
the response of Salmonella typhi is less than Salmonella para typhi,
this may be due to genetic factor that found in Salmonella typhi (which
make it produce more poly saccharide rather than Salmonella para typhi).[4][19] Interestingly
from this research the inhibition zones of effervescent tablets are greater than conventional
tablets that may be an indication for more activity and may have quicker using response or
action.[5][19]
Keywords: Salmonella typhi, Salmonella para typhi, Effervescent ciprofloxacin HCl, response, Activity.
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