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Abstract

A REVIEW ON STUDY OF FORMULATING CREAMS THROUGH TRANSDERMAL DRUG DELIVERY SYSTEM.

Shilpi Kashyap* and Nidhi Dhiman

ABSTRACT

Structure of the skin: Skin is most extensive and readily accessible organ in the body. Its chief functions are concern with protection, temperature regulation, control of water output and sensation. In an average adult it covers an area of about 1.73m2 and receives one third of circulating blood through the body at any given time. The potential of using intact skin as the site of administration for dermatological preparations to elicit pharmacological action in the skin tissue has been recognized for several years. Until the turn of the century, the skin was thought to be impermeable.

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