WJPPS Citation

Login

Search

News & Updation

  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  
  • New Impact Factor
  • WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

  • WJPPS: MARCH ISSUE PUBLISHED
  • March Issue has been successfully launched on 1 March 2024.

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • Scope Indexed
  • WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

Abstract

SEPARATION AND SIMULTANEOUS DETERMINATION OF PROLINE AND ENOXACIN IN HUMAN URINE BY CAPILLARY ELECTROPHORESIS WITH ELECTROCHEMILUMINESCENCE

Xiao Guo, Ming Su* and Hanwen Sun

ABSTRACT

The coupling of Ru(bpy)32+ based electrochemiluminescence(ECL) detection with capillary electrophoresis(CE) was developed for the simultaneous determination of proline and enoxacin in human urine. The effects of experimental conditions including the mode of applied voltage signal, the potential of working electrode, pH value, the flow rate of carrier of solution and the concentration of Ru(bpy)32+ and the ECL intensity of the drugs were investigated in detail. Parameters related to the separation and detection were investigated and optimized. Under optimized conditions the proposed method displayed a linear range from 0.2 to 80 μg mL–1 for proline and 0.1 to 100 μg mL–1 for enoxacin. Their limits of detection were 0.06 and 0.02 μg mL–1, respectively. A baseline separation for proline and enoxacin was achieved within 10 min. Developed method was successfully applied to determine proline and enoxacin in human urine.

Keywords: Electrochemiluminescence; Capillary electrophoresis; Proline; Enoxacin; Human urine.


[Download Article]     [Download Certifiate]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More