Abstract

ORAL SUBMUCOUS FIBROSIS: A COMPARATIVE CLINICO-HISTOPATHOLOGICAL STUDY AMONG THE POPULATION OF PATNA.

Dr. Jazib Nazeer*, Dr. Rohit Singh, Dr. Supriya Singh, Dr. Abhishek Kumar, Dr. Tanoj Kumar and Dr. Avanindra Kumar

ABSTRACT

Introduction: Oral submucous fibrosis (OSF) is a precancerous condition associated with the use of betel/areca nut in various forms. It is characterized by restricted mouth opening, tongue protrusion and cheek rigidity. Aim and Objective: To correlate the clinical staging with histopathological grading in OSF patients. Materials and Methods: A hospital-based study at Patna Dental College, Patna was done on 200 OSF cases. A detailed history of each patient was recorded along with clinical examination. Punch biopsy was performed for histopathological correlation. Clinical staging of the disease in terms of the ability to open one’s mouth was correlated with histopathological grading. Results: The male to female ratio of OSF cases was 5:1. All forms of areca nut products were associated with OSF. Chewing of panmasala was associated with early presentation of OSF as compared to chewing of other products of areca nut. Conclusion: statistical analysis showed that there is no significant correlation between clinical staging and histopathological grading. The possibility of difference in the severity and extent of fibrosis in different regions of the oral mucosa and involved muscles were considered as contributory factors for this variation.

Keywords: Oral submucous histopathological with OSF.