Abstract

A STUDY OF VITAMIN D LEVELS IN PATIENTS OF CORONARY ARTERY DISEASE

Dr. Nitin Tyagi*, Aroop Mohanty, Charanjeet Kaur, Ankita Kabi, Supriti Kumari, Mamta, Sugandha Sharma, Sunita Rani, Dhananjay Kumar Sahu, Jagdish Prasad,
Bhaskar Charana Kabi

ABSTRACT

Background: Coronary Artery Disease (CAD) is a major global health problem. Recent studies demonstrated that lower vitamin D level (<30ng/ml) is associated with higher blood pressure and directly or indirectly with CAD, due to vascular endothelial damage. However the results are inconsistent. Aims and objectives: To find the association between 25(OH) vitamin D serum levels and coronary artery disease risk. Materials and Methods: In this case control study, we compared Vitamin D levels in 120 subjects with angiographically proven coronary artery disease with those of 120 age and sex matched healthy controls. Serum 25(OH) vitamin D levels were estimated by ELISA. Data was collected and analysed by suitable statistical methods. Result: Levels of 25(OH) vitamin D were 11.7±1.06 ng/ml in cases as compared to 24.3±1.54 ng/ml in controls (p value <0.0001). Conclusion: There is a strong inverse association between 25(OH) vitamin D serum levels and coronary artery disease risk.

Keywords: Vitamin D, coronary artery disease.