Abstract

ANTHELMINTIC ACTIVITY OF MITRAGYNA PARVIFOLIA (ROXB) KORTH FRUIT EXTRACT

Supriya N. Mandrupkar*, Ravina R. Pawar, Mandar J. Bhandwalkar, Dr. Rajendra C. Doijad

ABSTRACT

The present research programme was aimed to investigate the anthelmintic activity of the aqueous extract of Mitragyana Parvifolia (Roxb).korth fruit against adult Indian earthworm Pheritimaposthuma. Methanol ðanol extract of dried fruit was used for the study. The ethanolic extract of M. Parvifolia fruit at the concentration of 100 mg/ml showed significant anthelmintic activity, whereas lower concentration 20 mg/ml did not produce significant results when compared with Piperazine citrate standard. The result of anthelmintic activity of methanolic & ethanolic extract produced were evaluated by observing paralysis time and death time of earthworms and were found to be dose dependent. This finding proves usefulness of fruit as an anthelmintic drug.

Keywords: Mitragyna Parvifolia, Rubiaceae, Anthelmintic activity.