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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

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New Impact Factor

WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

Scope Indexed

WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: APRIL ISSUE PUBLISHED

April Issue has been successfully launched on 1 April 2024.

Abstract

METHOD DEVELOPMENT AND VALIDATION FOR THE ESTIMATION OF OFLOXACIN AND NITAZOXANIDE PRESENT IN BULK & TABLET BY SIMULTANEOUS EQUATION METHOD USING UV-SPECTROPHOTOMETRY

N. Vijayalakshmi*, S.K. Abdul Feroz, Ch. Naga Manasa and P. Jaswanthi

ABSTRACT

Ofloxacin and Nitazoxanide are estimated simultaneously in bulk and tablets by U.V spectrophotometric Simultaneous equation method. This method employs simultaneous equation for analysis, using Sodium hydroxide as solvent. The two wavelengths 288.88 nm (λmax of ofloxacin) and 227.99 (λmax of Nitazoxanide) were selected for simultaneous equation. Linearity was observed in the concentration of 0.3-0.9 μg/ml for Ofloxacin and0.3-0.9 μg/ml for Nitazoxanide. Statistical analysis and recovery studies validated the method. This method utilised three groups of samples and two sampling wavelengths as 288.88 nm and 227.99 nm. Standard solutions of three group samples of both the drugs were prepared and concentrations were determined.

Keywords: Simultaneous equation method, Paired t-test, Ofloxacin, Nitazoxanide.

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